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Matrix Degradation in Human Immunodeficiency Virus Type 1–Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study

BACKGROUND: Extensive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in HI...

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Detalles Bibliográficos
Autores principales: Walker, Naomi F, Wilkinson, Katalin A, Meintjes, Graeme, Tezera, Liku B, Goliath, Rene, Peyper, Janique M, Tadokera, Rebecca, Opondo, Charles, Coussens, Anna K, Wilkinson, Robert J, Friedland, Jon S, Elkington, Paul T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815569/
https://www.ncbi.nlm.nih.gov/pubmed/28475709
http://dx.doi.org/10.1093/cid/cix231