Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment

Despite of multitude investigations no reliable prognostic immunohistochemical biomarkers in GIST have been established so far with added value to predict the recurrence risk of high risk GIST besides mitotic count, primary location and size. In this study, we analyzed the prognostic relevance of ei...

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Detalles Bibliográficos
Autores principales: Ihle, Michaela Angelika, Huss, Sebastian, Jeske, Wiebke, Hartmann, Wolfgang, Merkelbach-Bruse, Sabine, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Sihto, Harri, Sundby Hall, Kirsten, Eriksson, Mikael, Reichardt, Peter, Joensuu, Heikki, Wardelmann, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815598/
https://www.ncbi.nlm.nih.gov/pubmed/29451912
http://dx.doi.org/10.1371/journal.pone.0193048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815598/
https://www.ncbi.nlm.nih.gov/pubmed/29451912
http://dx.doi.org/10.1371/journal.pone.0193048

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