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Adaptive Mutations in RNA Polymerase and the Transcriptional Terminator Rho Have Similar Effects on Escherichia coli Gene Expression

Modifications to transcriptional regulators play a major role in adaptation. Here, we compared the effects of multiple beneficial mutations within and between Escherichia coli rpoB, the gene encoding the RNA polymerase β subunit, and rho, which encodes a transcriptional terminator. These two genes h...

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Detalles Bibliográficos
Autores principales: González-González, Andrea, Hug, Shaun M., Rodríguez-Verdugo, Alejandra, Patel, Jagdish Suresh, Gaut, Brandon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815632/
https://www.ncbi.nlm.nih.gov/pubmed/28961910
http://dx.doi.org/10.1093/molbev/msx216