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Simultaneous Polymerization and Polypeptide Particle Production via Reactive Spray-Drying

[Image: see text] A method for producing polypeptide particles via in situ polymerization of N-carboxyanhydrides during spray-drying has been developed. This method was enabled by the development of a fast and robust synthetic pathway to polypeptides using 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as...

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Detalles Bibliográficos
Autores principales: Glavas, Lidija, Odelius, Karin, Albertsson, Ann-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815657/
https://www.ncbi.nlm.nih.gov/pubmed/27445061
http://dx.doi.org/10.1021/acs.biomac.6b00747