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Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult CMs, partially due to their withdrawal from the cell cycle. Here, we show that microRNA-128 (miR-128) is upregulated...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Feng, Yuliang, Liang, Jialiang, Yu, Hao, Wang, Cheng, Wang, Boyu, Wang, Mingyang, Jiang, Lin, Meng, Wei, Cai, Wenfeng, Medvedovic, Mario, Chen, Jenny, Paul, Christian, Davidson, W. Sean, Sadayappan, Sakthivel, Stambrook, Peter J., Yu, Xi-Yong, Wang, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816015/
https://www.ncbi.nlm.nih.gov/pubmed/29453456
http://dx.doi.org/10.1038/s41467-018-03019-z