Utility of Glioblastoma Patient-Derived Orthotopic Xenografts in Drug Discovery and Personalized Therapy

Despite substantial effort and resources dedicated to drug discovery and development, new anticancer agents often fail in clinical trials. Among many reasons, the lack of reliable predictive preclinical cancer models is a fundamental one. For decades, immortalized cancer cell cultures have been used...

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Detalles Bibliográficos
Autores principales: Patrizii, Michele, Bartucci, Monica, Pine, Sharon R., Sabaawy, Hatem E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816058/
https://www.ncbi.nlm.nih.gov/pubmed/29484285
http://dx.doi.org/10.3389/fonc.2018.00023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816058/
https://www.ncbi.nlm.nih.gov/pubmed/29484285
http://dx.doi.org/10.3389/fonc.2018.00023

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