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The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery

BACKGROUND: Inflammasome-mediated activation of caspase-1 regulates inflammatory responses and pyroptosis. We analyzed possible associations between inflammasome-related genes and immune reconstitution in HIV-infected antiretroviral therapy (ART)-treated patients. METHODS: Cross-sectional, case–cont...

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Detalles Bibliográficos
Autores principales: Bandera, Alessandra, Masetti, Michela, Fabbiani, Massimiliano, Biasin, Mara, Muscatello, Antonio, Squillace, Nicola, Clerici, Mario, Gori, Andrea, Trabattoni, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816335/
https://www.ncbi.nlm.nih.gov/pubmed/29483915
http://dx.doi.org/10.3389/fimmu.2018.00214