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Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota

BACKGROUND: Dysbiosis of the gut microbiota has been implicated in the pathogenesis of many autoimmune conditions including type 1 diabetes (T1D). It is unknown whether changes in the gut microbiota observed in T1D are due to environmental drivers, genetic risk factors, or both. Here, we have perfor...

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Detalles Bibliográficos
Autores principales: Mullaney, Jane A., Stephens, Juliette E., Costello, Mary-Ellen, Fong, Cai, Geeling, Brooke E., Gavin, Patrick G., Wright, Casey M., Spector, Timothy D., Brown, Matthew A., Hamilton-Williams, Emma E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816355/
https://www.ncbi.nlm.nih.gov/pubmed/29454391
http://dx.doi.org/10.1186/s40168-018-0417-4