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Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain
BACKGROUND: Polymerase δ-interacting protein 2 (Poldip2) is a multifunctional protein that regulates vascular extracellular matrix composition and matrix metalloproteinase (MMP) activity. The blood-brain barrier (BBB) is a dynamic system assembled by endothelial cells, basal lamina, and perivascular...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816395/ https://www.ncbi.nlm.nih.gov/pubmed/29452577 http://dx.doi.org/10.1186/s12974-017-1032-1 |