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Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation

The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane. It has also been reported to promote transcription from the viral LTR both directly and indirectly. Noticeably, the HIV-1 and SIV(mac23...

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Detalles Bibliográficos
Autores principales: Beraud, Cyprien, Lemaire, Morgane, Perez Bercoff, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816530/
https://www.ncbi.nlm.nih.gov/pubmed/29454367
http://dx.doi.org/10.1186/s12985-018-0941-7