A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK

Mycobacterium tuberculosis, the etiological agent of the infectious disease tuberculosis, kills approximately 1.5 million people annually, while the spread of multidrug-resistant strains is of great global concern. Thus, continuous efforts to identify new antitubercular drugs as well as novel target...

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Detalles Bibliográficos
Autores principales: Chiarelli, Laurent R., Mori, Giorgia, Orena, Beatrice Silvia, Esposito, Marta, Lane, Thomas, de Jesus Lopes Ribeiro, Ana Luisa, Degiacomi, Giulia, Zemanová, Júlia, Szádocka, Sára, Huszár, Stanislav, Palčeková, Zuzana, Manfredi, Marcello, Gosetti, Fabio, Lelièvre, Joël, Ballell, Lluis, Kazakova, Elena, Makarov, Vadim, Marengo, Emilio, Mikusova, Katarina, Cole, Stewart T., Riccardi, Giovanna, Ekins, Sean, Pasca, Maria Rosalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816626/
https://www.ncbi.nlm.nih.gov/pubmed/29453370
http://dx.doi.org/10.1038/s41598-018-21614-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816626/
https://www.ncbi.nlm.nih.gov/pubmed/29453370
http://dx.doi.org/10.1038/s41598-018-21614-4

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