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Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes

Tenomodulin (Tnmd) is a type II transmembrane glycoprotein predominantly expressed in tendons and ligaments. We found that scleraxis (Scx), a member of the Twist-family of basic helix-loop-helix transcription factors, is a transcriptional activator of Tnmd expression in tenocytes. During embryonic d...

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Detalles Bibliográficos
Autores principales: Shukunami, Chisa, Takimoto, Aki, Nishizaki, Yuriko, Yoshimoto, Yuki, Tanaka, Seima, Miura, Shigenori, Watanabe, Hitomi, Sakuma, Tetsushi, Yamamoto, Takashi, Kondoh, Gen, Hiraki, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816641/
https://www.ncbi.nlm.nih.gov/pubmed/29453333
http://dx.doi.org/10.1038/s41598-018-21194-3