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A role for tau in learning, memory and synaptic plasticity

Tau plays a pivotal role in the pathogenesis of neurodegenerative disorders: mutations in the gene encoding for tau (MAPT) are linked to Fronto-temporal Dementia (FTD) and hyper-phosphorylated aggregates of tau forming neurofibrillary tangles (NFTs) that constitute a pathological hallmark of Alzheim...

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Detalles Bibliográficos
Autores principales: Biundo, Fabrizio, Del Prete, Dolores, Zhang, Hong, Arancio, Ottavio, D’Adamio, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816660/
https://www.ncbi.nlm.nih.gov/pubmed/29453339
http://dx.doi.org/10.1038/s41598-018-21596-3