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A role for tau in learning, memory and synaptic plasticity
Tau plays a pivotal role in the pathogenesis of neurodegenerative disorders: mutations in the gene encoding for tau (MAPT) are linked to Fronto-temporal Dementia (FTD) and hyper-phosphorylated aggregates of tau forming neurofibrillary tangles (NFTs) that constitute a pathological hallmark of Alzheim...
Autores principales: | Biundo, Fabrizio, Del Prete, Dolores, Zhang, Hong, Arancio, Ottavio, D’Adamio, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816660/ https://www.ncbi.nlm.nih.gov/pubmed/29453339 http://dx.doi.org/10.1038/s41598-018-21596-3 |
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