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A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease

Enzymes CYP4A11 and CYP4F2 are involved in biosynthesis of vasoactive 20-hydroxyeicosatetraenoic acid and may contribute to pathogenesis of coronary artery disease (CAD). We investigated whether polymorphisms of the CYP4A11 and CYP4F2 genes are associated with the risk of CAD in Russian population....

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Detalles Bibliográficos
Autores principales: Sirotina, Svetlana, Ponomarenko, Irina, Kharchenko, Alexander, Bykanova, Marina, Bocharova, Anna, Vagaytseva, Kseniya, Stepanov, Vadim, Churnosov, Mikhail, Solodilova, Maria, Polonikov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816861/
https://www.ncbi.nlm.nih.gov/pubmed/29484037
http://dx.doi.org/10.1155/2018/5812802