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Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice

Cognitive dysfunction and decreased mobility from aging and neurodegenerative conditions, such as Parkinson and Alzheimer diseases, are major biomedical challenges in need of more effective therapies. Increasing brain resilience may represent a new treatment strategy. Klotho, a longevity factor, enh...

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Detalles Bibliográficos
Autores principales: Leon, Julio, Moreno, Arturo J., Garay, Bayardo I., Chalkley, Robert J., Burlingame, Alma L., Wang, Dan, Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816951/
https://www.ncbi.nlm.nih.gov/pubmed/28793260
http://dx.doi.org/10.1016/j.celrep.2017.07.024