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Facile Fabrication of Reduction-Responsive Supramolecular Nanoassemblies for Co-delivery of Doxorubicin and Sorafenib toward Hepatoma Cells

Combination of doxorubicin with sorafenib (SF) was reported to be a promising strategy for treating hepatocellular carcinoma (HCC). In this study, we designed a reduction-responsive supramolecular nanosystem based on poly (ethylene glycol)-β-cyclodextrin (PEG-CD) and a disulfide-containing adamantin...

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Detalles Bibliográficos
Autores principales: Xiong, Qingqing, Cui, Mangmang, Yu, Ge, Wang, Jian, Song, Tianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816960/
https://www.ncbi.nlm.nih.gov/pubmed/29487523
http://dx.doi.org/10.3389/fphar.2018.00061