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Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A(2) Proves Renal Origins of Urinary PGI-M and TX-M

The balance between vascular prostacyclin, which is antithrombotic, and platelet thromboxane A(2), which is prothrombotic, is fundamental to cardiovascular health. Prostacyclin and thromboxane A(2) are formed after the concerted actions of cPLA(2)α (cytosolic phospholipase A(2)) and COX (cyclooxygen...

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Detalles Bibliográficos
Autores principales: Mitchell, Jane A., Knowles, Rebecca B., Kirkby, Nicholas S., Reed, Daniel M., Edin, Matthew L., White, William E., Chan, Melissa V., Longhurst, Hilary, Yaqoob, Magdi M., Milne, Ginger L., Zeldin, Darryl C., Warner, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816977/
https://www.ncbi.nlm.nih.gov/pubmed/29298774
http://dx.doi.org/10.1161/CIRCRESAHA.117.312144