From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity

Recent advances in next-generation sequencing and other omics technologies capable to map cell fate provide increasing evidence on the crucial role of intra-tumor heterogeneity (ITH) for cancer progression. The different facets of ITH, from genomic to microenvironmental heterogeneity and the hierarc...

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Detalles Bibliográficos
Autores principales: Gambara, Guido, Gaebler, Manuela, Keilholz, Ulrich, Regenbrecht, Christian R. A., Silvestri, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817069/
https://www.ncbi.nlm.nih.gov/pubmed/29491834
http://dx.doi.org/10.3389/fphar.2018.00077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817069/
https://www.ncbi.nlm.nih.gov/pubmed/29491834
http://dx.doi.org/10.3389/fphar.2018.00077

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