Oligopeptide Targeting Sortase A as Potential Anti-infective Therapy for Staphylococcus aureus

Sortase A (SrtA)-catalyzed anchorage of surface proteins in most Gram-positive bacteria is indispensable for their virulence, suggesting that this transpeptidase is a promising target for antivirulence therapy. Here, an oligopeptide, LPRDA, was identified as an effective inhibitor of SrtA via virtua...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Li, Hongen, Pan, Juan, Dong, Jing, Zhou, Xuan, Niu, Xiaodi, Deng, Xuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817083/
https://www.ncbi.nlm.nih.gov/pubmed/29491861
http://dx.doi.org/10.3389/fmicb.2018.00245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817083/
https://www.ncbi.nlm.nih.gov/pubmed/29491861
http://dx.doi.org/10.3389/fmicb.2018.00245

Ejemplares similares