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Structure Based Virtual Screening Studies to Identify Novel Potential Compounds for GPR142 and Their Relative Dynamic Analysis for Study of Type 2 Diabetes

GPR142 (G protein receptor 142) is a novel orphan GPCR (G protein coupled receptor) belonging to “Class A” of GPCR family and expressed in β cells of pancreas. In this study, we reported the structure based virtual screening to identify the hit compounds which can be developed as leads for potential...

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Detalles Bibliográficos
Autores principales: Kaushik, Aman C., Kumar, Sanjay, Wei, Dong Q., Sahi, Shakti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817085/
https://www.ncbi.nlm.nih.gov/pubmed/29492402
http://dx.doi.org/10.3389/fchem.2018.00023