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Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport

Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, which may present different sensitivity to treatment....

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Detalles Bibliográficos
Autores principales: da Costa, Kelli Monteiro, Valente, Raphael C., Salustiano, Eduardo J., Gentile, Luciana B., Freire-de-Lima, Leonardo, Mendonça-Previato, Lucia, Previato, José O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817095/
https://www.ncbi.nlm.nih.gov/pubmed/29491856
http://dx.doi.org/10.3389/fmicb.2018.00205