Cargando…

The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS

OBJECTIVE(S): Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A. Rich fruits on some apoptotic and autophagy genes in human gastric cancer cell line AGS. MATERIALS AND METHODS: Using quantitative...

Descripción completa

Detalles Bibliográficos
Autores principales: Jafargholizadeh, Naser, Zargar, Seyed Jalal, Aftabi, Younes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817168/
https://www.ncbi.nlm.nih.gov/pubmed/29511491
http://dx.doi.org/10.22038/ijbms.2018.25175.6236