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The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS
OBJECTIVE(S): Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A. Rich fruits on some apoptotic and autophagy genes in human gastric cancer cell line AGS. MATERIALS AND METHODS: Using quantitative...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817168/ https://www.ncbi.nlm.nih.gov/pubmed/29511491 http://dx.doi.org/10.22038/ijbms.2018.25175.6236 |