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MiR-9-5p and miR-106a-5p dysregulated in CD4(+) T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation

OBJECTIVE(S): Multiple sclerosis (MS) is considered as a chronic type of an inflammatory disease characterized by loss of myelin of CNS. Recent evidence indicates that Interleukin 17 (IL-17)-producing T helper cells (Th17 cells) population are increased and regulatory T cells (Treg cells) are decrea...

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Detalles Bibliográficos
Autores principales: Majd, Maryam, Hosseini, Aref, Ghaedi, Kamran, Kiani-Esfahani, Abbas, Tanhaei, Somayeh, Shiralian-Esfahani, Hanieh, Rahnamaee, Seyed Yahya, Mowla, Seyed Javad, Nasr-Esfahani, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817171/
https://www.ncbi.nlm.nih.gov/pubmed/29511494
http://dx.doi.org/10.22038/ijbms.2018.25382.6275