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Characterization of feedback-resistant mevalonate kinases from the methanogenic archaeons Methanosaeta concilii and Methanocella paludicola
The inhibition of mevalonate kinase (MVK) by downstream metabolites is an important mechanism in the regulation of isoprenoid production in a broad range of organisms. The first feedback-resistant MVK was previously discovered in the methanogenic archaeon Methanosarcinamazei. Here, we report the clo...
Autores principales: | Kazieva, Ekaterina, Yamamoto, Yoko, Tajima, Yoshinori, Yokoyama, Keiichi, Katashkina, Joanna, Nishio, Yousuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817203/ https://www.ncbi.nlm.nih.gov/pubmed/28869407 http://dx.doi.org/10.1099/mic.0.000510 |
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