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Effects of Long‐Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats

BACKGROUND: Reduced dopamine D2 receptor (D2R) ligand binding has repeatedly been demonstrated in the striatum of humans with alcohol use disorder (AUD). The attenuated D2R binding has been suggested to reflect a reduced D2R density, which in turn has been proposed to drive craving and relapse. Howe...

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Detalles Bibliográficos
Autores principales: Feltmann, Kristin, Borroto‐Escuela, Dasiel Oscar, Rüegg, Joëlle, Pinton, Luca, de Oliveira Sergio, Thatiane, Narváez, Manuel, Jimenez‐Beristain, Antonio, Ekström, Tomas J., Fuxe, Kjell, Steensland, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817245/
https://www.ncbi.nlm.nih.gov/pubmed/29205397
http://dx.doi.org/10.1111/acer.13568