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Effects of a Single Dose of Parecoxib on Inflammatory Response and Ischemic Tubular Injury Caused by Hemorrhagic Shock in Rats

Parecoxib, a selective COX-2 inhibitor, is used to improve analgesia in postoperative procedures. Here we evaluated whether pretreatment with a single dose of parecoxib affects the function, cell injury, and inflammatory response of the kidney of rats subjected to acute hemorrhage. Inflammatory resp...

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Detalles Bibliográficos
Autores principales: Takaku, Mariana, da Silva, Andre Carnevali, Iritsu, Nathalie Izumi, Vianna, Pedro Thadeu Galvao, Castiglia, Yara Marcondes Machado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817310/
https://www.ncbi.nlm.nih.gov/pubmed/29535870
http://dx.doi.org/10.1155/2018/8375746