Melatonin Modulation of Sirtuin-1 Attenuates Liver Injury in a Hypercholesterolemic Mouse Model

Hypercholesterolemia increases and exacerbates stress signals leading also to liver damage (LD) and failure. Sirtuin1 (SIRT1) is involved in lifespan extension and it plays an essential role in hepatic lipid metabolism. However, its involvement in liver hypercholesterolemic damage is not yet complet...

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Detalles Bibliográficos
Autores principales: Bonomini, Francesca, Favero, Gaia, Rodella, Luigi Fabrizio, Moghadasian, Mohammed H., Rezzani, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817311/
https://www.ncbi.nlm.nih.gov/pubmed/29516009
http://dx.doi.org/10.1155/2018/7968452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817311/
https://www.ncbi.nlm.nih.gov/pubmed/29516009
http://dx.doi.org/10.1155/2018/7968452

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