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Association of CTH variant with sinusoidal obstruction syndrome in children receiving intravenous busulfan and cyclophosphamide before hematopoietic stem cell transplantation

Sinusoidal obstruction syndrome (SOS) is a severe complication of hematopoietic stem cell transplantation (HSCT) that can be fatal, often attributed to the conditioning regimen prior to HSCT. We evaluated the association of SOS risk with gene variants in cystathionase (CTH), an enzyme involved in gl...

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Detalles Bibliográficos
Autores principales: Huezo-Diaz Curtis, P, Uppugunduri, C R S, Muthukumaran, J, Rezgui, M A, Peters, C, Bader, P, Duval, M, Bittencourt, H, Krajinovic, Maja, Ansari, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817388/
https://www.ncbi.nlm.nih.gov/pubmed/27779248
http://dx.doi.org/10.1038/tpj.2016.65