A systems biology approach to investigate the mechanism of action of trabectedin in a model of myelomonocytic leukemia

This study was designed to investigate the mode of action of trabectedin in myelomonocytic leukemia cells by applying systems biology approaches to mine gene expression profiling data and pharmacological assessment of the cellular effects. Significant enrichment was found in regulons of target genes...

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Detalles Bibliográficos
Autores principales: Mannarino, L, Paracchini, L, Craparotta, I, Romano, M, Marchini, S, Gatta, R, Erba, E, Clivio, L, Romualdi, C, D’Incalci, M, Beltrame, L, Pattini, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817395/
https://www.ncbi.nlm.nih.gov/pubmed/27958379
http://dx.doi.org/10.1038/tpj.2016.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817395/
https://www.ncbi.nlm.nih.gov/pubmed/27958379
http://dx.doi.org/10.1038/tpj.2016.76

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