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Scalable Access to Arylomycins via C–H Functionalization Logic

[Image: see text] Arylomycins are a promising class of “latent” antibacterial natural products currently in preclinical development. Access to analogues within this family has previously required a lengthy route involving multiple functional group manipulations that is costly and time-intensive on s...

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Detalles Bibliográficos
Autores principales: Peters, David S., Romesberg, Floyd E., Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817625/
https://www.ncbi.nlm.nih.gov/pubmed/29381350
http://dx.doi.org/10.1021/jacs.8b00087