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KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target

Lung neoplasms are the leading cause of death by cancer worldwide. Non-small cell lung cancer (NSCLC) constitutes more than 80% of all lung malignancies and the majority of patients present advanced disease at onset. However, in the last decade, multiple oncogenic driver alterations have been discov...

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Detalles Bibliográficos
Autores principales: Román, Marta, Baraibar, Iosune, López, Inés, Nadal, Ernest, Rolfo, Christian, Vicent, Silvestre, Gil-Bazo, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817724/
https://www.ncbi.nlm.nih.gov/pubmed/29455666
http://dx.doi.org/10.1186/s12943-018-0789-x