Role of Bruton’s tyrosine kinase in B cells and malignancies

Bruton’s tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic signaling that is critical for proliferation and survival of leukemic cells in many B cell malignancies. BTK was initially shown to be defective in the primary immunodeficiency X-linked agammaglobulinemia...

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Detalles Bibliográficos
Autores principales: Pal Singh, Simar, Dammeijer, Floris, Hendriks, Rudi W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817726/
https://www.ncbi.nlm.nih.gov/pubmed/29455639
http://dx.doi.org/10.1186/s12943-018-0779-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817726/
https://www.ncbi.nlm.nih.gov/pubmed/29455639
http://dx.doi.org/10.1186/s12943-018-0779-z

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