Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo

BACKGROUND: Traumatic brain injury (TBI) is a critical public health and socioeconomic problem throughout the world. Inflammation-induced secondary injury is one of the vital pathogenic parameters of TBI. Molecular signaling cascades of pyroptosis, a specific type of cellular necrosis, are key drive...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Chen, Yuhua, Meng, Jiao, Wu, Minfei, Bi, Fangfang, Chang, Cuicui, Li, Hua, Zhang, Liangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817788/
https://www.ncbi.nlm.nih.gov/pubmed/29458437
http://dx.doi.org/10.1186/s12974-018-1083-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817788/
https://www.ncbi.nlm.nih.gov/pubmed/29458437
http://dx.doi.org/10.1186/s12974-018-1083-y

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