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Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo

BACKGROUND: Traumatic brain injury (TBI) is a critical public health and socioeconomic problem throughout the world. Inflammation-induced secondary injury is one of the vital pathogenic parameters of TBI. Molecular signaling cascades of pyroptosis, a specific type of cellular necrosis, are key drive...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Chen, Yuhua, Meng, Jiao, Wu, Minfei, Bi, Fangfang, Chang, Cuicui, Li, Hua, Zhang, Liangjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817788/ https://www.ncbi.nlm.nih.gov/pubmed/29458437 http://dx.doi.org/10.1186/s12974-018-1083-y

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