Mechanisms of receptor tyrosine kinase activation in cancer

Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes including growth, motility, differentiation, and metabolism. As such, dysregulation of RTK signaling leads to an assortment of human diseases, most notably, cancers. Recent large-scale genomic studies have rev...

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Detalles Bibliográficos
Autores principales: Du, Zhenfang, Lovly, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817791/
https://www.ncbi.nlm.nih.gov/pubmed/29455648
http://dx.doi.org/10.1186/s12943-018-0782-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817791/
https://www.ncbi.nlm.nih.gov/pubmed/29455648
http://dx.doi.org/10.1186/s12943-018-0782-4

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