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Mechanisms of receptor tyrosine kinase activation in cancer
Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes including growth, motility, differentiation, and metabolism. As such, dysregulation of RTK signaling leads to an assortment of human diseases, most notably, cancers. Recent large-scale genomic studies have rev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817791/ https://www.ncbi.nlm.nih.gov/pubmed/29455648 http://dx.doi.org/10.1186/s12943-018-0782-4 |