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The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells
BACKGROUND: EGFR-dependent cell migration plays an important role in lung cancer progression. Our previous study observed that the HECT E3 ubiquitin ligase NEDD4 is significantly correlated with tumor metastasis and required for migration and invasion signaling of EGFR in gastric cancer cells. Howev...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817799/ https://www.ncbi.nlm.nih.gov/pubmed/29455656 http://dx.doi.org/10.1186/s12943-018-0784-2 |