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The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

BACKGROUND: EGFR-dependent cell migration plays an important role in lung cancer progression. Our previous study observed that the HECT E3 ubiquitin ligase NEDD4 is significantly correlated with tumor metastasis and required for migration and invasion signaling of EGFR in gastric cancer cells. Howev...

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Detalles Bibliográficos
Autores principales: Shao, Genbao, Wang, Ranran, Sun, Aiqin, Wei, Jing, Peng, Ke, Dai, Qian, Yang, Wannian, Lin, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817799/
https://www.ncbi.nlm.nih.gov/pubmed/29455656
http://dx.doi.org/10.1186/s12943-018-0784-2