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Role and targeting of anaplastic lymphoma kinase in cancer

Anaplastic lymphoma kinase (ALK) gene activation is involved in the carcinogenesis process of several human cancers such as anaplastic large cell lymphoma, lung cancer, inflammatory myofibroblastic tumors and neuroblastoma, as a consequence of fusion with other oncogenes (NPM, EML4, TIM, etc) or gen...

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Detalles Bibliográficos
Autores principales: Della Corte, Carminia Maria, Viscardi, Giuseppe, Di Liello, Raimondo, Fasano, Morena, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Morgillo, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817803/
https://www.ncbi.nlm.nih.gov/pubmed/29455642
http://dx.doi.org/10.1186/s12943-018-0776-2