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Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

OBJECTIVE: Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of mTOR pathway after cerebral ischemia–reperfusion injury in rats. METHODS: Longa's midd...

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Detalles Bibliográficos
Autores principales: Wu, Meiling, Zhang, Huadan, Kai, Jiejing, Zhu, Feng, Dong, Jingyin, Xu, Ziwei, Wong, Michael, Zeng, Ling‐Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817831/
https://www.ncbi.nlm.nih.gov/pubmed/29468175
http://dx.doi.org/10.1002/acn3.507