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Retrograde interferon‐gamma signaling induces major histocompatibility class I expression in human‐induced pluripotent stem cell‐derived neurons

OBJECTIVE: Injury‐associated axon‐intrinsic signals are thought to underlie pathogenesis and progression in many neuroinflammatory and neurodegenerative diseases, including multiple sclerosis (MS). Retrograde interferon gamma (IFN γ) signals are known to induce expression of major histocompatibility...

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Detalles Bibliográficos
Autores principales: Clarkson, Benjamin D. S., Patel, Misha S., LaFrance‐Corey, Reghann G., Howe, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817842/
https://www.ncbi.nlm.nih.gov/pubmed/29468178
http://dx.doi.org/10.1002/acn3.516