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Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

Tyrosine kinases belong to a family of enzymes that mediate the movement of the phosphate group to tyrosine residues of target protein, thus transmitting signals from the cell surface to cytoplasmic proteins and the nucleus to regulate physiological processes. Non-receptor tyrosine kinases (NRTK) ar...

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Detalles Bibliográficos
Autores principales: Siveen, Kodappully S., Prabhu, Kirti S., Achkar, Iman W., Kuttikrishnan, Shilpa, Shyam, Sunitha, Khan, Abdul Q., Merhi, Maysaloun, Dermime, Said, Uddin, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817858/
https://www.ncbi.nlm.nih.gov/pubmed/29455667
http://dx.doi.org/10.1186/s12943-018-0788-y