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Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products
Tyrosine kinases belong to a family of enzymes that mediate the movement of the phosphate group to tyrosine residues of target protein, thus transmitting signals from the cell surface to cytoplasmic proteins and the nucleus to regulate physiological processes. Non-receptor tyrosine kinases (NRTK) ar...
Autores principales: | Siveen, Kodappully S., Prabhu, Kirti S., Achkar, Iman W., Kuttikrishnan, Shilpa, Shyam, Sunitha, Khan, Abdul Q., Merhi, Maysaloun, Dermime, Said, Uddin, Shahab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817858/ https://www.ncbi.nlm.nih.gov/pubmed/29455667 http://dx.doi.org/10.1186/s12943-018-0788-y |
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