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Advances in studies of tyrosine kinase inhibitors and their acquired resistance

Protein tyrosine kinase (PTK) is one of the major signaling enzymes in the process of cell signal transduction, which catalyzes the transfer of ATP-γ-phosphate to the tyrosine residues of the substrate protein, making it phosphorylation, regulating cell growth, differentiation, death and a series of...

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Detalles Bibliográficos
Autores principales: Jiao, Qinlian, Bi, Lei, Ren, Yidan, Song, Shuliang, Wang, Qin, Wang, Yun-shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817861/
https://www.ncbi.nlm.nih.gov/pubmed/29455664
http://dx.doi.org/10.1186/s12943-018-0801-5