Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

Multidrug resistance (MDR) triggered by ATP binding cassette (ABC) transporter such as ABCB1, ABCC1, ABCG2 limited successful cancer chemotherapy. Unfortunately, no commercial available MDR modulator approved by FDA was used in clinic. Tyrosine kinase inhibitors (TKIs) have been administrated to fig...

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Detalles Bibliográficos
Autores principales: Wu, Shaocong, Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817862/
https://www.ncbi.nlm.nih.gov/pubmed/29455646
http://dx.doi.org/10.1186/s12943-018-0775-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817862/
https://www.ncbi.nlm.nih.gov/pubmed/29455646
http://dx.doi.org/10.1186/s12943-018-0775-3

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