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Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors

Searching for targets that allow pharmacological inhibition of cell proliferation in over-proliferative states, such as cancer, leads us to finely understand the complex mechanisms orchestrating the perfect control of mitosis number, frequency and pace as well as the molecular arrangements that indu...

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Detalles Bibliográficos
Autores principales: Montor, Wagner Ricardo, Salas, Andrei Ronaldo Oliveira Silva Escartin, Melo, Fabiana Henriques Machado de
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817866/
https://www.ncbi.nlm.nih.gov/pubmed/29455659
http://dx.doi.org/10.1186/s12943-018-0792-2