Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer’s Disease Pathology in Down Syndrome

BACKGROUND: Down syndrome (DS; trisomy 21) individuals have a spectrum of hematopoietic and neuronal dysfunctions and by the time they reach the age of 40 years, almost all develop Alzheimer’s disease (AD) neuropathology which includes senile plaques and neurofibrillary tangles. Inflammation and inn...

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Detalles Bibliográficos
Autores principales: Raha-Chowdhury, Ruma, Henderson, James W., Raha, Animesh Alexander, Stott, Simon R.W., Vuono, Romina, Foscarin, Simona, Wilson, Liam, Annus, Tiina, Fincham, Robert, Allinson, Kieren, Devalia, Vinod, Friedland, Robert P., Holland, Anthony, Zaman, Shahid H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817909/
https://www.ncbi.nlm.nih.gov/pubmed/29278889
http://dx.doi.org/10.3233/JAD-170814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817909/
https://www.ncbi.nlm.nih.gov/pubmed/29278889
http://dx.doi.org/10.3233/JAD-170814

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