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The force-dependent mechanism of DnaK-mediated mechanical folding
It is well established that chaperones modulate the protein folding free-energy landscape. However, the molecular determinants underlying chaperone-mediated mechanical folding remain largely elusive, primarily because the force-extended unfolded conformation fundamentally differs from that character...
Autores principales: | Perales-Calvo, Judit, Giganti, David, Stirnemann, Guillaume, Garcia-Manyes, Sergi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817926/ https://www.ncbi.nlm.nih.gov/pubmed/29487911 http://dx.doi.org/10.1126/sciadv.aaq0243 |
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