In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis

The three-dimensional architecture of the pancreatic islet is integral to beta cell function, but the process of islet formation remains poorly understood due to the difficulties of imaging internal organs with cellular resolution. Within transparent zebrafish larvae, the developing pancreas is rela...

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Detalles Bibliográficos
Autores principales: Freudenblum, Julia, Iglesias, José A., Hermann, Martin, Walsen, Tanja, Wilfinger, Armin, Meyer, Dirk, Kimmel, Robin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818004/
https://www.ncbi.nlm.nih.gov/pubmed/29386244
http://dx.doi.org/10.1242/dev.158477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818004/
https://www.ncbi.nlm.nih.gov/pubmed/29386244
http://dx.doi.org/10.1242/dev.158477

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