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In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis
The three-dimensional architecture of the pancreatic islet is integral to beta cell function, but the process of islet formation remains poorly understood due to the difficulties of imaging internal organs with cellular resolution. Within transparent zebrafish larvae, the developing pancreas is rela...
Autores principales: | Freudenblum, Julia, Iglesias, José A., Hermann, Martin, Walsen, Tanja, Wilfinger, Armin, Meyer, Dirk, Kimmel, Robin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818004/ https://www.ncbi.nlm.nih.gov/pubmed/29386244 http://dx.doi.org/10.1242/dev.158477 |
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